Van de Ven Brace Ends Everton's Run at Brand New Stadium
Micky van de Ven became the initial defender to net twice in a English top-flight match for Spurs since the Belgian defender in March 2013.
At a glance
Micky Van de Ven heads into the net two times in first half
Everton's defender has goal disallowed after video check
Pape Matar Sarr scores final goal in 89th minute
The defeat is the Merseyside club's first at their new ground
Micky van de Ven scored on two occasions as Spurs extended their unbeaten run in away games in the Premier League and delivered Everton their initial loss at their new home.
Everton were undefeated in their last five matches at their recently opened stadium at Bramley-Moore Dock, having departed Goodison Park behind after more than a century at the end of last season.
But Tottenham's leader Van de Ven struck twice from set-pieces in the opening 45 minutes to place their impressive record at jeopardy, and they were failed to turn it around before the midfielder - assisted by former Toffees attacker the Brazilian - headed home a third to put the game to bed.
The Everton defender thought he had levelled the scores a short while after the defender's first goal, directing a bullet header past Guglielmo Vicario from an Everton corner.
Beto, in the meantime, failed to convert a number of chances, while the Italian goalkeeper made a succession of excellent stops to guarantee the London club went five matches on the road without defeat in the Premier League.
But the video assistant referee intervened, advising the match official to review the goal on the screen and the referee decided that the winger and Iliman Ndiaye were in offside positions and had impeded with the Tottenham goalkeeper.
This victory moves Thomas Frank's team up to third in the division, a handful of points off north London rivals and leaders Arsenal.
Everton remain 14th and sit six points ahead of the drop zone.
Tottenham analysis: Van de Ven fulfils role at each end of pitch
After a drab weekday display in the European competition against Monaco, where they mustered a only two shots on target, the manager opted for Randal Kolo Muani up front instead of former Toffees player Richarlison.
The new arrival was failed to make much of an impact before being replaced for the substitute after an hour on the pitch, but it turns out he wasn't needed in the end.
Centre-back the Dutchman transformed into an attacking force to be feared.
Spurs' opening strike came from a cleverly executed corner routine, with the midfielder directing the ball toward the face of goal for an unmarked the defender to score.
And the captain - stepping up as skipper in the Argentine's absence - notched his next goal in added time as he rose above the England keeper to nod in.
Van de Ven was just as impressive in defensive duties, partnering effectively with Kevin Danso as the pair dealt excellently with the numerous deliveries sent their way by Everton.
Everton analysis: Toffees missing striker's instinct
Everton's recent stadium had been a fortress, but it appears the freshness may have worn off slightly and fans headed to the gates after the midfielder's final goal for Tottenham.
The end in the team's unbeaten home run won't be a massive concern for the manager, but their attacking woes will be.
Beto and Thierno Barry - the Everton's two recognised centre-forwards - had netted just a single goal combined before Sunday's outing.
And they were unable to contribute to that poor record on a wet and gloomy night on Merseyside.
The striker's form was summed up when he chose to bicycle-kick a clear chance from near the goal, despite having room and opportunity to readjust for a more conventional shot that would have challenged Vicario.
The substitute, as well, was unable to influence the game after replacing the starter in the second half.
It was not for a shortage of opportunity. The majority of Everton's offensive moves came through the winger and the forward, who tirelessly delivered dangerous crosses into the Spurs penalty area.
What next for both teams?
The Toffees: Moyes' men head to the Stadium of Light in the top flight on early November at 8 PM.
Spurs: Spurs travel to Newcastle's ground on late October for their fourth-round League Cup match against the Magpies.